Manjaro Controversy: Unveiling the Risks of a Popular Drug
Manjaro, initially celebrated as a breakthrough medication for type 2 diabetes and weight loss, is now facing mounting lawsuits and scrutiny regarding its safety. This article will explore the potential risks associated with Manjaro, its applications, and the growing concerns surrounding its use.
What is Manjaro?
Manjaro, with the active ingredient terzepatide, is manufactured by Eli Lilly. It gained initial approval in the US for managing type 2 diabetes. Clinical trials also demonstrated significant weight loss, leading to its off-label use for obesity. In the US, terzepatide is marketed as Zepbound for weight loss and maintenance when combined with diet and exercise. Manjaro and Zepbound belong to a class of drugs known as GLP-1 receptor agonists, which also includes Ozempic and Wegovy (semaglutide).
Serious Side Effects and Legal Concerns
Despite its initial acclaim, Manjaro is now under legal and ethical scrutiny due to severe side effects. Lawsuits allege that the manufacturer failed to adequately warn users about potential serious risks. These risks include:
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Gastroparesis (Stomach Paralysis): A condition where the stomach muscles stop moving normally, leading to improper stomach emptying. This can be an excruciating condition with potential internal complications.
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Severe Gastrointestinal Obstruction (Intestinal Blockage): A rare but serious risk where the bowel becomes blocked or experiences ileus.
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Chronic Vomiting: Defined as daily vomiting lasting at least three weeks.
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Blood Clots: Including deep vein thrombosis (DVTs) and pulmonary embolism.
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Gallbladder Disease: Chronic gallbladder inflammation and the development of gallstones, potentially requiring surgical removal of the gallbladder.
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Gastroenteritis: An infection and inflammation of the digestive system, causing stomach cramps, diarrhea, and vomiting. The most concerning complication is dehydration.
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Pancreatitis: Swelling or inflammation of the pancreas.
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Vision Problems: A risk of blindness or vision impairment with GLP-1 medications.
Notably, the risks are considered exceptionally high when using Manjaro for weight loss due to the higher doses often involved.
Recent Developments: Blood Clots and a Tragic Death
Recent data in the US and UK has linked GLP-1 drugs to blood clots, raising further concerns about their safety. In the UK, a tragic case involved the death of Susan McGeown, a 58-year-old nurse, who passed away after taking two low-dose injections of terzepatide. Her family reported that she experienced severe stomach pain and organ failure shortly after starting the medication. Her death certificate cited multiple organ failure and pancreatitis as immediate causes, with terzepatide as a contributing factor.
The UK's Medicines and Healthcare products Regulatory Agency (MHRA) has reminded the public to report any side effects through the Yellow Card Scheme, emphasizing that new medications, even approved ones, are subject to ongoing safety monitoring.
Are Weight Loss Drugs Like Manjaro Safe?
While advocates argue that these medications offer life-changing benefits for individuals with obesity or diabetes, the potential risks, including rare and severe side effects, cannot be ignored.
Moving Forward
As lawsuits continue to unfold and a court trial is scheduled for 2025, the legal and medical communities are closely watching the ongoing situation surrounding Manjaro. If you're considering taking any new medication, it is crucial to discuss it with a trusted healthcare professional.